Diastereoselective synthesis of α-bromoamides leading to diastereomerically enriched α-amino-, α-hydroxy- and α-thiocarboxylic acid derivatives
✍ Scribed by Robert S. Ward; Andrew Pelter; Dominique Goubet; Martyn C. Pritchard
- Publisher
- Elsevier Science
- Year
- 1995
- Tongue
- English
- Weight
- 242 KB
- Volume
- 6
- Category
- Article
- ISSN
- 0957-4166
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📜 SIMILAR VOLUMES
Reported here is an efficient procedure for enantio-and diastereoselective synthesis of pure b-amino acids that display a tert-hydroxyl functionality in the a-position. Key steps include a catalytic asymmetric aldol reaction and a modified Curtius rearrangement to form oxazolidinone intermediates, w
Alkylation / Oxazolines / anti-α-Alkyl α-hydroxy β-amino acids / Lithium dianion / Penicillin G acylase As part of an ongoing project concerning the synthesis of conditions, affording in quantitative yield the corresponding hydroxy amides. The starting (R)-3-amino-3-phenyl-enantiomerically pure α-hy
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v