Diastereoselective Synthesis of Methylenecyclopropanes from Chiral Cyclopropene Derivatives
β Scribed by Zhe Yang; Xiaocong Xie; Joseph M. Fox
- Publisher
- John Wiley and Sons
- Year
- 2006
- Tongue
- English
- Weight
- 99 KB
- Volume
- 118
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
π SIMILAR VOLUMES
## Abstract LβAmino acids (LβAla, LβPhe, LβVal, LβPro) were used as a source of chirality in the diastereoselective synthesis of tetrahydroisoquinoline derivatives. The key step was the PictetβSpengler condensation of ketoamides **4** and **10**, which proceeded under very mild conditions. LβAla, L
Diastereoselective SmI 2 -Mediated Cascade Radical Cyclizations of Methylenecyclopropane Derivatives -A Synthesis of Paeonilactone B. -Using the title cascade reaction from (VII) to (IX) as key step the natural product paeonilactone B (XIV) is synthesized in an efficient manner. The relative stereoc