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Diastereoselective Synthesis of Indanes and Tetralins via Intramolecular Friedel–Crafts Reaction

✍ Scribed by Begouin, Jeanne-Marie; Capitta, Francesca; Wu, Xian; Niggemann, Meike

Book ID: 120019104
Publisher: American Chemical Society
Year: 2013
Tongue: English
Weight: 579 KB
Volume: 15
Category: Article
ISSN: 1523-7060
DOI: 10.1021/ol400341p

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## Abstract magnified image 1__H__‐Indeno[1,2‐__d__]pyrimidine‐2,5(3__H__,9b__H__)‐dione derivatives **2(a‐i)** and 2,3‐dihydro‐2‐thioxo‐1__H__‐indeno[1,2‐__d__]pyrimidine‐5(9b__H__)‐ones **2(j‐q)** were synthesized __via__ an intramolecular Friedel‐Crafts reaction between the aryl and ester group