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Diastereoselective Synthesis of 3,4-Dimethoxy-7-morphinanone: A Potential Route to Morphine

✍ Scribed by Yamada, Osamu; Ogasawara, Kunio


Book ID
127158485
Publisher
American Chemical Society
Year
2000
Tongue
English
Weight
69 KB
Volume
2
Category
Article
ISSN
1523-7060

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Preparation of 7,8-dimethoxy-3,4-dihydro
✍ A. M. El-Fishawy; D. J. Slatkin; J. E. Knapp; P. L. Schiff Jr. πŸ“‚ Article πŸ“… 1984 πŸ› John Wiley and Sons 🌐 English βš– 264 KB πŸ‘ 1 views

Oxidation of 7,8-dimethoxy-l,2,3,4-tetrahydroisquinoline with potassium permanganate in acetone afforded 7,8-dimethoxy-3,4-dihydroisoquinoline as the primary product. Hence, oxidation of the appropriate secondary nonphenolic 7,8-dioxygenated tetrahydroisoquinoline alkaloid is thus a facile method fo