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Diastereoselective Synthesis of 1,3-Disubstituted 1,2,3,4-Tetrahydro-β-carbolines Using Pictet-Spengler Reaction in Non-acidic Aprotic Media.

✍ Scribed by S. D. Sharma; Susmita Bhaduri; Gurpreet Kaur


Publisher
John Wiley and Sons
Year
2007
Weight
23 KB
Volume
38
Category
Article
ISSN
0931-7597

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ChemInform Abstract: Enantiospecific For
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Enantiospecific Formation of trans-1,3-Disubstituted Tetrahydro-βcarbolines by the Pictet-Spengler Reaction and Conversion of cis Diastereomers into Their trans Counterparts by Scission of the C-1/N-2 Bond. -The factors which effect the stereoselective formation of trans-products in the Pictet-Spen