Diastereoselective Rhodium-Catalyzed Ene-Cycloisomerization Reactions of Alkenylidenecyclopropanes: Total Synthesis of (−)-α-Kainic Acid
✍ Scribed by Evans, P. Andrew; Inglesby, Phillip A.
- Book ID
- 118063098
- Publisher
- American Chemical Society
- Year
- 2012
- Tongue
- English
- Weight
- 428 KB
- Volume
- 134
- Category
- Article
- ISSN
- 0002-7863
No coin nor oath required. For personal study only.
📜 SIMILAR VOLUMES
## Abstract The neurotoxin α‐kainic acid (**7**) was synthesized from **1** __via__ the thermal key step **5** → **6** in 41% overall yield.
A total synthetic route to (-)a-kainic acid has been developed based on the Pauson-Khand reaction as a key reaction for the construction of the bicycle ring system. The unique structure and novel biological activities (anthehninticl, insecticidal\* and neuroexitatory activity) of kainic acid l, iso
## Abstract ChemInform is a weekly Abstracting Service, delivering concise information at a glance that was extracted from about 100 leading journals. To access a ChemInform Abstract of an article which was published elsewhere, please select a “Full Text” option. The original article is trackable v