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Diastereoselective radical mediated alkylation of a chiral glycolic acid derivative

โœ Scribed by Abazi, Sokol; Rapado, Liliana Parra; Renaud, Philippe


Book ID
118054425
Publisher
Royal Society of Chemistry
Year
2011
Tongue
English
Weight
164 KB
Volume
9
Category
Article
ISSN
1477-0520

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## Diasterwselective akylation of chital lithium etwlates (dl-, (R)-and (S)-9) derivedjbm 4-t-butykycioh in the presence da chiral secondary amine (R)_I and litkium bromide was studied., It is shown that (R)-1 re t&a&s the direction of tke attack of electrophi~s. stereoselective axial attack ws oL e