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Diastereoselective oxidation of sulfides to sulfoxides. Synthesis of novel C-6 sulfoxy tetrahydromevinic acids

✍ Scribed by Kathleen M. Poss; Sam T. Chao; Eric M. Gordon; Peggy J. McCann; Dinos P. Santafianos; Sarah C. Traeger; Ravi K. Varma; William N. Washburn

Publisher: Elsevier Science
Year: 1994
Tongue: French
Weight: 279 KB
Volume: 35
Category: Article
ISSN: 0040-4039
DOI: 10.1016/s0040-4039(00)73210-2

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✦ Synopsis

The synthesis and diastereoselective oxidation of novel tetrahydromevinic acid lactone sulfies to sulfixide~ is described.

The enantio-and diastereoselective oxidation of sullkles to sulfoxides is an area of research currently under investigation in a number of laboratories. t-4 As part of our program to identify a potent and hepato-

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