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Diastereoselective Manipulations of Bicyclo[ m .1.0]alkane Derivatives. 2. Nucleophilic Additions to the Carbonyl Carbons of Bicyclo[ m .1.0]alkan-2-ones 1

โœ Scribed by Mash, Eugene A.; Gregg, Timothy M.; Kaczynski, Michelle A.


Book ID
126334409
Publisher
American Chemical Society
Year
1996
Tongue
English
Weight
310 KB
Volume
61
Category
Article
ISSN
0022-3263

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Diastereoselective manipulations of bicy
โœ Eugene A. Mash; Kalpana S. Nimkar; James A. Baron ๐Ÿ“‚ Article ๐Ÿ“… 1997 ๐Ÿ› Elsevier Science ๐ŸŒ French โš– 776 KB

Conformations of the title compound were studied using a Monte Carlo search technique. Two principal conformational motifs were observed for the bicyclic carbocycle in which both faces of the carbonyl appear susceptible to nucleophilic attack. The title compound was synthesized in eight steps from