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Diastereoselective Intermolecular Cobalt-Catalyzed Reductive Aldol Reactions of α,β-Unsaturated Amides with Ketones

✍ Scribed by Lumby, Ralph J. R.; Joensuu, Pekka M.; Lam, Hon Wai


Book ID
126216057
Publisher
American Chemical Society
Year
2007
Tongue
English
Weight
82 KB
Volume
9
Category
Article
ISSN
1523-7060

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✍ Juha Pulkkinen; Pompiliu S. Aburel; Nis Halland; Karl Anker Jørgensen 📂 Article 📅 2004 🏛 John Wiley and Sons 🌐 English ⚖ 97 KB 👁 2 views

## Abstract A chiral imidazolidine catalyst was shown to catalyze the highly enantio‐ and diastereoselective domino Michael‐aldol reaction of β‐diketone and β‐ketosulfone derivatives with α,β‐unsaturated ketones to form optically active cyclohexanones having three or four contiguous chiral centers.