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Diastereoselective .alpha.-Alkylation of 2-Acyl-3-phenyl-l-menthopyrazoles

✍ Scribed by Kashima, Choji; Fukuchi, Iwao; Hosomi, Akira


Book ID
127357076
Publisher
American Chemical Society
Year
1994
Tongue
English
Weight
493 KB
Volume
59
Category
Article
ISSN
0022-3263

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Conjugate addition of grignard reagents
✍ Choji Kashima; Katsumi Takahashi; Kiyoshi Fukusaka; Akira Hosomi 📂 Article 📅 1998 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 649 KB

## Abstract The conjugate additions of __N__‐(α,β‐unsaturated)acylpyrazoles were carried out by the treatment with Grignard reagents in the presence of cuprous halides. The reaction of 2‐(α,β‐unsaturated)acyl‐3‐phenyl‐__l__‐menthopyrazoles 3a‐h occurred in higher chemical yields and with asymmetric