Three-Center Diastereoselective Aldol Ad
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Dr. Johann Mulzer; Alexander Chucholowski
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Article
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1982
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John Wiley and Sons
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English
⚖ 226 KB
The a-hydroxyglycine 1 -readily accessible from glyoxylic acid hydrate and benzyl ~arbaminate[~I---was converted into the ethyl ether 2. Successive reaction with PCI3 and triethyl phosphite led to ethyl 2-benzyloxycarbonylamino-2-diethyloxyphosphorylacetate 3 (yield 80%). N-Acyl-2-(diethyloxyphospho