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Diastereoselective Access to Chiral Non-racemic [1,3]Oxazolo[2,3-a]isoindol-5-one Ring Systems via O-Cationic Cyclization.

✍ Scribed by Jana Sikoraiova; Abderrahim Chihab-Eddine; Stefan Marchalin; Adam Daich

Book ID
101937629
Publisher
John Wiley and Sons
Year
2010
Weight
31 KB
Volume
33
Category
Article
ISSN
0931-7597

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Diastereoselective access to chiral non-
Diastereoselective access to chiral non-racemic [1,3]oxazolo-[2,3-a]isoindol-5-one ring systems viaO-cationic cyclization
✍ Jana Sikoraiová; ŠTefan Marchalín; Abderrahim Chihab-Eddine; Adam Daïch 📂 Article 📅 2002 🏛 Journal of Heterocyclic Chemistry 🌐 English ⚖ 102 KB

## Abstract **Dedicated to Professor Jean Morel for his retirement** The title compounds **4** have been prepared from suitable β‐amino‐ alcohol **2** and phthalic anhydride (**5**) in a three‐step sequence in moderate to good yields (58‐94%). The key step of this methodology is based on an intram