Diastereoface-Selective Epoxidations: Dependency on the Reagent Electrophilicity
โ Scribed by Charles Fehr
- Book ID
- 101304146
- Publisher
- John Wiley and Sons
- Year
- 1998
- Tongue
- English
- Weight
- 94 KB
- Volume
- 37
- Category
- Article
- ISSN
- 0044-8249
No coin nor oath required. For personal study only.
๐ SIMILAR VOLUMES
The stereochemical results in an aldol reaction between the enolate 2 and various a-methyl aldehydes indicates a stabilizing through space interaction between C4-C s unsaturation and the formyl group. This interaction leads to a reaction conformation which favors a C7-C ~ (epothilone numbering) ant
In chlorinated ethylenes, the chlorine substitution exerts, by its electron withdrawal effect, a stabilization of the molecule which increases with the number auf chlorine residues. All chlorinated ethylenes are metabolically transformed, in a first step reaction, to epoxides which may rearrange to