Diamond-Blackfan anemia (DBA) is characterized by a variable response to corticosteroid therapy. Patients poorly responsive to acceptable doses of steroid treatment require long-term transfusion therapy. We have treated three patients with DBA with the immunosuppressive agent cyclosporin A with limi
β¦ LIBER β¦
Diamond Blackfan anemia: A paradigm for a ribosome-based disease
β Scribed by Steven R. Ellis; Amy Tabb Massey
- Book ID
- 116742907
- Publisher
- Elsevier Science
- Year
- 2006
- Tongue
- English
- Weight
- 131 KB
- Volume
- 66
- Category
- Article
- ISSN
- 0306-9877
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## Communicated by Johan den Dunnen Mutations in ribosomal proteins RPS19, RPS24 and RPS17 have been reported in Diamond-Blackfan Anemia (DBA), an autosomal dominant disease characterised by pure red cell aplasia. DBA is the prototype of ribosomapathies: a protein synthesis defect in a tissue with
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