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Dialogue between RhoA/ROCK and Members of the Par Complex in Cell Polarity

✍ Scribed by Raffaella Sordella; Linda Van Aelst

Book ID: 116404231
Publisher: Elsevier Science
Year: 2008
Tongue: English
Weight: 297 KB
Volume: 14
Category: Article
ISSN: 1534-5807
DOI: 10.1016/j.devcel.2008.01.015

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## Abstract **Background:** Recent studies have revealed that aPKC (atypical protein kinase C), PAR‐3 and PAR‐6 play indispensable roles in the regulation of various cell polarization events, from worms to mammals, suggesting that they comprise an evolutionarily conserved protein machinery which is