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Diagnostic yield of stimulation and voluntary single-fiber electromyography in myasthenia gravis

✍ Scribed by Leopoldo Murga; Fernando Sánchez; Carmen Menéndez; José M. Castilla


Publisher
John Wiley and Sons
Year
1998
Tongue
English
Weight
70 KB
Volume
21
Category
Article
ISSN
0148-639X

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✦ Synopsis


Voluntary and stimulation single-fiber electromyography were performed in the extensor digitorum communis muscle of 15 myasthenic patients. The increase in mean and individual mean consecutive difference as well as the proportion of blocking in the volitional activation were greater than in the stimulation method. These differences may be explained in part by the different degree of alteration in large as compared with small motor units in patients with myasthenia gravis.


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Extraocular muscle weakness is the most common presenting sign of myasthenia gravis (MG). More than half of patients presenting with symptoms isolated to these muscles (OMG) develop generalized myasthenia gravis (GMG) over the course of their illness. No clinical, laboratory, or electrophysiological