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Diagnostic Value of KRAS Mutation in Evaluation of Synchronous or Metachronous Pancreatic and Lung Adenocarcinomas

โœ Scribed by Chen, Xiaowei; Mansukhani, Mahesh; Borczuk, Alain; Singh, Bahadur; He, Huangjun; Hamele-Bena, Diane

Book ID
125468988
Publisher
Elsevier
Year
2013
Tongue
English
Weight
487 KB
Volume
2
Category
Article
ISSN
2213-2945

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Prognostic value of loss of heterozygosi
Prognostic value of loss of heterozygosity and KRAS2 mutations in lung adenocarcinoma
โœ Laura De Gregorio; Giacomo Manenti; Matteo Incarbone; Silvana Pilotti; Ugo Pasto ๐Ÿ“‚ Article ๐Ÿ“… 1998 ๐Ÿ› John Wiley and Sons ๐ŸŒ French โš– 89 KB

The prognostic values of loss of heterozygosity (LOH) at loci frequently involved in non-small cell lung cancer and of KRAS2 gene mutations were studied in lung adenocarcinoma patients. LOHs were relatively common, ranging from 24% at chromosome 10p to 55% at chromosome 17p13. KRAS2 mutations at cod