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Diagnostic value of FibroTest with normal serum aminotransferases

โœ Scribed by Thierry Poynard; Mona Munteanu; Yen Ngo; Mercedes Torres; Yves Benhamou; Dominique Thabut; Vlad Ratziu

Book ID
102239064
Publisher
John Wiley and Sons
Year
2006
Tongue
English
Weight
64 KB
Volume
43
Category
Article
ISSN
0270-9139

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โœฆ Synopsis

prospectively the concordance between FibroScan and FibroTest in 100 consecutive HCV patients with normal ALT levels. Liver elasticity measurements could not be obtained in 3 patients. In the remaining 97 patients (34 male, 63 female; mean age 55 ฯฎ 14 years), the median FibroScan value was 4.9 kPa (range 2.6-13.3). Concordance between FibroScan and FibroTest for significant fibrosis (METAVIR F2-F3-F4) was 67%, using either a cutoff of 7.1 kPa or 8.7 kPa (Table 1).

In conclusion, we believe combining FibroScan and FibroTest as a first-line noninvasive assessment of liver fibrosis might prove particularly useful in the setting of HCV carriers with normal ALT levels and should be further evaluated.

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