Diagnostic Molecular Pathology in Practice: A Case-Based Approach

✍ Scribed by Ruth A. Heim (auth.), Iris Schrijver (eds.)

• Publisher: Springer-Verlag Berlin Heidelberg
• Year: 2011
• Tongue: English
• Leaves: 351
• Edition: 1
• Category: Library

✦ Synopsis

The specialty of molecular genetic pathology (MGP) focuses on the molecular identification of inherited genetic conditions, acquired genetic diseases, and infectious diseases. This entirely case-based book covers a broad cross-section of the practical issues frequently encountered in the day-to-day activities of a molecular genetic pathologist. The book is divided into four sections on the principal areas addressed in MGP: inherited diseases, hematopathology, solid tumors, and infectious diseases. The topics covered by the cases in each section include test selection, qualitative and quantitative laboratory techniques, test interpretation, prognostic and therapeutic considerations, ethical considerations, technical troubleshooting, and result reporting. This book is designed for trainees in MGP and clinical molecular genetics who require a practice-based preparation for board examinations. It will also be very useful for residents and fellows in medical specialties to which MGP is pertinent, and for practicing pathologists who want to learn more about the current practice of molecular diagnostics.

✦ Table of Contents

Front Matter....Pages i-xi
Front Matter....Pages 1-1
Cystic Fibrosis....Pages 3-8
Alport Syndrome....Pages 9-15
Alpha Thalassemia....Pages 17-22
Charcot-Marie-Tooth Disease....Pages 23-28
Hearing Loss....Pages 29-34
Polycystic Kidney Disease....Pages 35-41
Fragile X Syndrome....Pages 43-48
Malignant Hyperthermia....Pages 49-55
Rh Incompatibility....Pages 57-63
Pharmacogenetics....Pages 65-72
Front Matter....Pages 73-73
B-Cell Lymphoma....Pages 75-83
T-Cell Lymphoma....Pages 85-92
Posttransplant Lymphoproliferative Disorder....Pages 93-104
HIV-Associated Hodgkin Lymphoma....Pages 105-112
Chronic Myelogenous Leukemia....Pages 113-122
Myeloproliferative Neoplasms....Pages 123-131
Acute Myeloid Leukemia: FLT3 / NPM1 ....Pages 133-139
Acute Myeloid Leukemia: CEBPA ....Pages 141-146
Bone Marrow Engraftment Analysis....Pages 147-157
Mixed Phenotype Acute Leukemia....Pages 159-165
Front Matter....Pages 167-167
Breast Cancer....Pages 169-176
Lung Adenocarcinoma....Pages 177-183
Melanoma....Pages 185-192
Thyroid Cancer....Pages 193-200
Renal Cell Carcinoma....Pages 201-207
Gastrointestinal Stromal Tumor....Pages 209-216
Lynch Syndrome....Pages 217-225
Oligodendroglioma....Pages 227-232
Glioblastoma Multiforme....Pages 233-241
Carcinoma of Unknown Primary....Pages 243-249
Front Matter....Pages 251-251
Human Immunodeficiency Virus....Pages 253-260
Cytomegalovirus....Pages 261-267
Human Papillomavirus....Pages 269-275
Chlamydia trachomatis....Pages 277-282
MRSA....Pages 283-291
Influenza A (H1N1)....Pages 293-298
Bordetella pertussis....Pages 299-305
Human Metapneumovirus....Pages 307-313
BK Virus....Pages 315-320
Respiratory Viruses....Pages 321-328
Back Matter....Pages 329-339

✦ Subjects

Pathology; Oncology