Diagnostic efficacy of bone scintigraphy, magnetic resonance imaging, and positron emission tomography in bone metastases of myxoid liposarcoma

✍ Scribed by Carlos Conill; Xavier Setoain; Luis Colomo; Antonio Palacín; Andreu Combalia-Aleu; Jaime Pomés; Jordi Marruecos; Mauricio Vargas; Joan Maurel

• Publisher: John Wiley and Sons
• Year: 2008
• Tongue: English
• Weight: 553 KB
• Volume: 27
• Category: Article
• ISSN: 1053-1807
• DOI: 10.1002/jmri.21298

✦ Synopsis

Abstract

Myxoid liposarcomas (MLS) have a tendency to metastasize to unusual sites. We report an unusual case of bone metastases not detected by bone scan and neither by fluorodeoxyglucose positron emission tomography (PET‐FDG) and successfully identified with magnetic resonance imaging (MRI) in a patient with metachronic MLS. Histopathological examination of the primary tumor evidenced a tumor with unfavorable prognostic markers, and the biopsy of an iliac bone lesion confirmed the diagnosis of metastatic disease. On histological grounds, the tumor showed features of a more differentiated neoplasm without foci of round cells or necrosis in the latter. MRI allowed the identification of disseminated disease compared to computed tomography (CT) and PET scans. Thus, because of the heterogeneous histological features of MLS and the biolog‐ical behavior of the disease, a combined approach of FDGPET‐CT and MRI, may allow a more accurate staging of soft tissue sarcomas. J. Magn. Reson. Imaging 2008;27:625–628. © 2008 Wiley‐Liss, Inc.