Diagnostic devices with microfluidics

✍ Scribed by Francesco Piraino, Šeila Selimović

• Publisher: CRC Press
• Year: 2017
• Tongue: English
• Leaves: 281
• Series: Devices circuits and systems
• Edition: 1
• Category: Library

✦ Synopsis

This book provides a current view of the research and commercial landscape of diagnostics devices, particularly those that utilize microscale technologies, intended for both patient and laboratory use. Common diagnostic devices that are based on microfluidic principles include glucose sensors for diabetic patients and over-the-counter pregnancy tests. Other diagnostic devices are being developed to quickly test a patient for bacterial and viral infections, and other diseases. The chapters, written by experts from around the world, discuss how to fabricate, apply, and market microfluidic diagnostic chips – for lab and at-home use. Most importantly, the book also contains a discussion of topics relevant to the private sector, including patient-focused, market-oriented development of diagnostics devices.

✦ Table of Contents

Content: Cover
Half Title
Series Page
Title Page
Copyright Page
Table of Contents
Preface
Series Editor
Editors
Contributors
Section I: Microfluidic Devices for Diagnostics
Chapter 1: Handheld Microfluidics for Point-of-Care In Vitro Diagnostics
1.1 Introduction 1.2 Design of the Handheld Microfluidic System 1.2.1 Pneumatic Subsystem
1.2.2 Pressure Stabilization in Reservoirs 1 and 2
1.2.3 Microcontroller-Based Electronic Subsystem
1.2.4 Android Application 1.2.5 Microfluidic Device Design and Fabrication, Reagent Containers, and Interfaces 1.2.6 Simulated Bead-Based Fluorescence Immunoassay Liquid Handling
1.3 System Performance
1.3.1 Pneumatic Subsystem
1.3.2 Microbead-Based HIV p24 Immunoassay
1.3.3 Power Consumption 1.4 Summary Acknowledgments
References
Chapter 2: Body-Worn Microfluidic Sensors
2.1 Introduction
2.2 Methods and Technologies for Collecting, Sensing, and Detection
2.2.1 Closed System Designs
2.2.2 Open System Designs for Biofluid Analysis 2.3 Potential Applications of Wearable Microfluidic Devices for Monitoring Bodily Fluids 2.3.1 Aural, Ocular, Oral, and Respiratory Fluids
2.3.2 Analysis of Skin Secretions
2.3.3 Bodily Fluids from the Genitourinary System
2.4 Conclusions and Future Directions
References

✦ Subjects

Medical instruments and apparatus.;Microfluidics.;SCIENCE / Biotechnology