Diagnostic classification of urothelial cells in urine cytology specimens using exclusively spectral information
✍ Scribed by Jaganath, Rajesh ;Angeletti, Cesar ;Levenson, Richard ;Rimm, David L.
- Publisher
- John Wiley and Sons
- Year
- 2004
- Tongue
- English
- Weight
- 212 KB
- Volume
- 102
- Category
- Article
- ISSN
- 0008-543X
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✦ Synopsis
BACKGROUND.
Although cytologic evaluation of urine specimens is a standard procedure in the diagnosis and follow-up of bladder carcinoma, its sensitivity and specificity are low. Cytopathologic diagnoses are driven primarily by spatial relations or morphology. Although color enhances the pathologist's perception of the specimen, spectral information plays a minimal role in diagnostic processes.
Recently, methods have been developed to capture and analyze spectral information from clinical specimens. In the current study, the authors determined the classification value of spectral information by testing its ability to discriminate between malignant and benign urothelial cells in cytology specimens.