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Diagnostic assay of chromium (VI) in the ex vivo fluid of the urine of a smoker using a fluorine-doped handmade sensor

✍ Scribed by Suw Young Ly; Min Joon Kim


Book ID
102311302
Publisher
John Wiley and Sons
Year
2009
Tongue
English
Weight
260 KB
Volume
23
Category
Article
ISSN
0887-8013

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✦ Synopsis


Abstract

A voltammetric diagnosis of a chromium (VI) ion was investigated using a fluorine‐doped graphite pencil electrode. Square wave (SW) stripping working conditions were attained at a high range of 0.051–0.45 mg L^−1^ and a microrange of 0.05–0.4 µg L^−1^ in a 0.1 M NH~4~H~2~PO~4~ electrolyte solution, at a relative standard deviation of 1.68% (RSD, n=15), using 10.0 µg L^−1^ Cr(VI). A fast experimental time was used only for the 120 sec SW accumulation time. An analytical detection‐limit (DL) of 0.008 µg L^−1^ was attained. DL appeared to be more sensitive than common voltammetric and spectrophotometric assays. The developed sensor was applied to tap water and the urine of a smoker. It was found that the methods can be applicable for in vivo fluid or medicinal diagnosis. J. Clin. Lab. Anal. 23:82–87, 2009. © 2009 Wiley‐Liss, Inc.