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Diagnostic and prognostic values of anti glucose-6-phosphate isomerase antibodies in community-recruited patients with very early arthritis

✍ Scribed by F. JOUEN; O. VITTECOQ; F. LEGUILLOU; I. TABTI-TITON; J. F. MENARD; O. MEJJAD; S. POUPLIN; P. BOUMIER; P. FARDELLONE; A. GAYET; D. GILBERT; F. TRON; X. LE LOËT

Book ID: 108698929
Publisher: John Wiley and Sons
Year: 2004
Tongue: English
Weight: 127 KB
Volume: 137
Category: Article
ISSN: 0009-9104
DOI: 10.1111/j.1365-2249.2004.02552.x

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Low prevalence of antibodies to glucose-6-phosphate isomerase in patients with rheumatoid arthritis and a spectrum of other chronic autoimmune disorders

✍ Isao Matsumoto; David M. Lee; Raphaela Goldbach-Mansky; Takayuki Sumida; Carol A 📂 Article 📅 2003 🏛 John Wiley and Sons 🌐 English ⚖ 300 KB 👁 2 views

## Abstract ## Objective Arthritis in the K/BxN mouse model results from pathogenic immunoglobulins that recognize glucose‐6‐phosphate isomerase (GPI), a glycolytic enzyme residing in the cytoplasm of all cells. Antibodies directed against GPI can, alone, transfer arthritis to healthy recipients.