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Diagnostic and prognostic role of matrix metalloproteases in cancer

✍ Scribed by Vihinen, Pia; Ala-aho, Risto; Kähäri, Veli-Matti

Book ID
121404883
Publisher
Informa plc
Year
2008
Tongue
English
Weight
442 KB
Volume
2
Category
Article
ISSN
1753-0059

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## Abstract Matrix metalloproteases (MMPs) are a collection of enzymes capable of cleaving extracellular matrix components, growth factors, and cell‐surface receptors. MMPs modulate most aspects of tumorigenesis and are highly expressed in cancer compared with normal tissues. Preclinical studies ha