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Diagnostic and pathogenetic role of antineutrophil cytoplasmic autoantibodies

✍ Scribed by J.iřina Bartůňková; Vladimír Tesař; Anna Šedivá


Book ID
117792879
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
207 KB
Volume
106
Category
Article
ISSN
1090-2341

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Objective. To investigate the pathogenetic role of antineutrophil cytoplasmic antibodies (ANCA) in Wegener's granulomatosis (WG). Methods. BALBlc mice were immunized with human IgG ANCA from a patient with WG. Control mice were immunized with normal human IgG. Levels of mouse ANCA and other autoant