Diagnostic accuracy of high-resolution MRI using a microscopy coil for patients with presumed DCIS following mammography screening
✍ Scribed by Jingzhi Zhu; Yasuyuki Kurihara; Yoshihide Kanemaki; Haruki Ogata; Mamoru Fukuda; Yasuo Nakajima; Ichiro Maeda
- Publisher
- John Wiley and Sons
- Year
- 2007
- Tongue
- English
- Weight
- 555 KB
- Volume
- 25
- Category
- Article
- ISSN
- 1053-1807
No coin nor oath required. For personal study only.
✦ Synopsis
Abstract
Purpose
To prospectively evaluate the accuracy of high‐resolution (HR)‐MRI as a secondary examination in women with abnormal calcifications detected on mammography.
Materials and Methods
We used a 4.7‐cm microscopy coil to acquire HR‐MRI signal data. We examined 52 women with breast lesions preoperatively using HR‐MRI and vacuum‐assisted core needle biopsy. The lesions were suspicious of malignancy, classified as category 3–5 on mammography (Breast Imaging Reporting and Data System [BI‐RADS]), and without a palpable mass. All visualized suspicious lesions were correlated with histological findings. We compared the HR‐MRI and pathological findings and calculated the sensitivity, specificity, and accuracy.
Results
We compared the breast HR‐MRI results with the gold standard of pathological results for studies of malignancy (DCIS and invasive cancer), and found a sensitivity of 88.5%, specificity of 92.3%, and accuracy of 90.4%. The positive predictive value (PPV) was 92%, and the negative predictive value (NPV) was 88.9%. When breast MRI was compared with pathological results for studies that diagnosed DCIS only, the results revealed a sensitivity of 88.6%, specificity of 88.2%, accuracy of 88.5%, PPV of 93.9%, and NPV of 78.9%.
Conclusion
HR‐MRI using a microscopy coil is a useful, reliable, safe, and minimally invasive procedure that is a good choice for secondary assessment of abnormal calcification in the breast. J. Magn. Reson. Imaging 2007. © 2006 Wiley‐Liss, Inc.