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Diagnostic accuracy of blood B-cell subset profiling and autoimmunity markers in Sjögren’s syndrome

✍ Scribed by Cornec, Divi; Saraux, Alain; Pers, Jacques-Olivier; Jousse-Joulin, Sandrine; Marhadour, Thierry; Roguedas-Contios, Anne-Marie; Genestet, Steeve; Renaudineau, Yves; Devauchelle-Pensec, Valérie


Book ID
121560373
Publisher
BioMed Central
Year
2014
Tongue
English
Weight
252 KB
Volume
16
Category
Article
ISSN
1478-6354

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## Abstract Using monoclonal antibodies to cell surface antigens, we studied lymphocyte subsets in 15 patients with primary Sjögren's syndrome. The absolute number of OKT8‐positive cells (reactive with T suppressor/cytotoxic cells) was significantly decreased in such patients (353 ± 186/mm^3^) comp