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Diagnosis of Sanfilippo type A syndrome by estimation of sulfamidase activity using a radiolabelled tetrasaccharide substrate

โœ Scribed by John J. Hopwood; Helen Elliott


Book ID
115823896
Publisher
Elsevier Science
Year
1982
Tongue
English
Weight
635 KB
Volume
123
Category
Article
ISSN
0009-8981

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๐Ÿ“œ SIMILAR VOLUMES


PRENATAL DIAGNOSIS OF SANFILIPPO A SYNDR
โœ W. J. KLEIJER; E. A. KARPOVA; G. C. GEILEN; J. L. M. KEULEMANS; J. G. M. HUIJMAN ๐Ÿ“‚ Article ๐Ÿ“… 1996 ๐Ÿ› John Wiley and Sons ๐ŸŒ English โš– 538 KB

We have investigated the use of a 4-methylumbelliferone (MU)-derived artificial substrate, MU-a-D-Nsulphoglucosaminide, for the sulphamidase assay in chorionic villi and amniotic fluid cells. In the new two-step enzyme assay, fluorescent MU is released by the successive action of endogenous sulphami