Pulse-chase experiments measuring 35S-sulphate incorporation into acid mucopolysaccharides were performed in the presence and absence of fructose 1-phosphate on fibroblasts obtained from one skin-biopsy of 25 obligate Hunter carriers. The presence of fructose 1-phosphate significantly increased the
✦ LIBER ✦
Diagnosis of Hunter's syndrome carriers; Radioactive sulphate incorporation into fibroblasts in the presence of fructose 1-phosphate
✍ Scribed by Tønne Tønnesen; Claus Lykkelund; Flemming Güttler
- Publisher
- Springer
- Year
- 1982
- Tongue
- English
- Weight
- 496 KB
- Volume
- 60
- Category
- Article
- ISSN
- 0340-6717
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Fibroblast cultures from 49 possible Hunter disease carriers were collected. These cultures were analysed for the incorporation of 35S-sulphate into acid mucopolysaccharides in the presence and the absence of fructose 1-phosphate. For 10 of these women more than one abnormal result was observed, whe