Background. Gestational trophoblastic disease consists of a group of interrelated diseases, including molar pregnancy, placental site trophoblastic tumor, and choriocarcinoma. Methods. Advances in the diagnosis and management of gestational trophoblastic: diseases over the past 5 years were reviewe
Diagnosis and management of gestational trophoblastic disease
โ Scribed by John L. Lewis Jr.
- Publisher
- John Wiley and Sons
- Year
- 1993
- Tongue
- English
- Weight
- 990 KB
- Volume
- 71
- Category
- Article
- ISSN
- 0008-543X
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Alternating 5-day chemotherapy with methotrexate and dactinomycin as primary therapy for nonmetastatic gestational trophoblastic disease was studied in nine patients. The complete response rate was 100% with follow-up of a median of 80 months. Stomatitis was universal but rarely prevented oral alime
Mitochondrial DNA (mtDNA) mutations have been implicated in a wide range of human disease. However, its role in gestational trophoblastic disease remains unclear. In this study, the entire mitochondrial genome of 10 hydatidiform moles (HM) and one choriocarcinoma were examined by automated DNA seque