Do We Need New Antidepressants?
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I. Hindmarch
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Article
📅
1997
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John Wiley and Sons
🌐
English
⚖ 136 KB
Tolerability and ecacy are important factors determining the choice of an antidepressant. Older tricyclic antidepressants (TCAs) are associated with signi®cant behavioural toxicity, notably psychomotor and cognitive impairment and sedation. These eects are not seen with newer TCAs and selective sero