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Diabetic retinopathy in Euro-Brazilian type 2 diabetic patients: relationship with polymorphisms in the aldose reductase, the plasminogen activator inhibitor-1 and the methylenetetrahydrofolate reductase genes

✍ Scribed by Katia G. Santos; Balduino Tschiedel; João Schneider; Katia Souto; Israel Roisenberg


Book ID
117370692
Publisher
Elsevier Science
Year
2003
Tongue
English
Weight
159 KB
Volume
61
Category
Article
ISSN
0168-8227

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## Abstract ## Background Poor glycaemic control, hypertension and duration of diabetes are risk factors for the development of diabetic nephropathy, but there may be genetic factors. Recently, a common C to T mutation at nucleotide position 677 of the MTHFR gene (MTHFR677C > T) has been reported