Diabetic nephropathy in American Indians, with a special emphasis on the pima Indians
β Scribed by Meda E. Pavkov; William C. Knowler; Robert L. Hanson; Robert G. Nelson
- Publisher
- Current Science Inc.
- Year
- 2008
- Tongue
- English
- Weight
- 279 KB
- Volume
- 8
- Category
- Article
- ISSN
- 1534-4827
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## Objective: To review data on the long-term effects of prenatal exposure to the diabetic intrauterine environment in the pima indians of arizona. this population has high rates of type 2 diabetes mellitus that has a strong genetic component and develops at young ages. ## Methods: Since 1965, pi
Segregation analysis suggests that the high prevalence of non-insulin-dependent diabetes mellitus in Pima Indians may be partially due to a single locus with a major effect on age of onset. A simulation study was conducted to evaluate the power of various age-adjustment strategies in linkage analysi