Diabetes Mellitus Volume 83 || Analysis of Insulin-Stimulated Glucose Uptake in Differentiated 3T3-L1 Adipocytes
✍ Scribed by �zcan, Sabire
- Book ID
- 121430713
- Publisher
- Humana Press
- Year
- 2003
- Tongue
- English
- Weight
- 98 KB
- Category
- Article
- ISBN-13
- 9781592593774
No coin nor oath required. For personal study only.
✦ Synopsis
Leading Researchers And Clinical Investigators Describe Their Best Cutting-edge Techniques For Studying, At Both The Molecular And Biochemical Levels, The Defects In Insulin Production And Action Associated With Diabetes.
📜 SIMILAR VOLUMES
## Abstract We used nigericin, a K^+^/H^+^ exchanger, to test whether glucose transport in 3T3‐L1 adipocytes was modulated by changes in intracellular pH. Our results showed that nigericin increased basal but decreased insulin‐stimulated glucose uptake in a time‐ and dose‐dependent manner. Whereas
It is well established that somatotropin (GH) antagonizes insulin action in vivo and that supraphysiologic concentrations of GH frequently result in insulin resistance and glucose intolerance. However, the demonstration of an anti-insulin activity by GH in vitro has been difficult. This study, there