We showed previously that a mutation in the mitochondria1 tRNAL"(UUR' gene at position 3243 associates with maternally inherited diabetes and deafness (MIDD). This mutation shows heteroplasmy in DNA from peripheral blood and other tissues. To examine whether heteroplasmy levels in peripheral blood D
Diabetes mellitus associated with mitochondrial myopathy and schizophrenia: a possible link between diabetes mellitus and schizophrenia
β Scribed by Odawara, M.; Isaka, M.; Tada, K.; Mizusawa, H.; Yamashita, K.
- Publisher
- John Wiley and Sons
- Year
- 1997
- Tongue
- English
- Weight
- 97 KB
- Volume
- 14
- Category
- Article
- ISSN
- 0742-3071
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Type 2 (non-insulin dependent) diabetes mellitus may be inherited along the maternal line and a variety of mitochondrial DNA (mtDNA) variants have been implicated in the pathogenesis. We have previously reported mutations in five regions of the mitochondrial genome which encompass 11 of the 22 tRNA
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