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Diabetes mellitus and vasopressin sensitive diabetes insipidus

✍ Scribed by Padrón, Rubén S. ;Amaro, Sergio ;Licea, Manuel ;Hung, Santiago ;González, Julio ;Acosta, Oscar Mateo


Book ID
110565132
Publisher
Springer-Verlag
Year
1980
Weight
274 KB
Volume
17
Category
Article
ISSN
0001-5563

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X-linked recessive nephrogenic diabetes insipidus is caused by mutations in the gene encoding the V2 vasopressin receptor (V2R), the mediator of the antidiuretic effect of arginine vasopressin (AVP) in mammalian kidneys. Upon binding to AVP, the receptor activates the G protein G s , stimulating a p