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Diabetes in pregnancy: Islet cell proliferation in the fetal rat pancreas

โœ Scribed by I. Swenne; U. Eriksson


Publisher
Springer
Year
1982
Tongue
English
Weight
454 KB
Volume
23
Category
Article
ISSN
0012-186X

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Fetal pancreatic development was measured in terms of total organ DNA and insulin concentration (ng/migrogram DNA) in the offspring of rats made mildly diabetic by intraperitoneal streptozotocin injection (60 mg/kg) on the first and second day of life. On day 20 the mean pancreatic insulin concentra

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The distribution of different celltypes (A, B, D and PP cells) of the endocrine pancreas was studied in both the normal and in the experimental diabetic non-pregnant and pregnant rat. In the normal rat the head (juxta duodenal part) of the pancreas contained more PP cells than the tail (12.5 +/- 1.1