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Diabetes in Pediatric Patients with Kearns-Sayre Syndrome: Clinical Presentation of 2 Cases and a Review of Pathophysiology

✍ Scribed by Ho, Josephine; Pacaud, Danièle; Rakic, Maja; Khan, Aneal


Book ID
125821166
Publisher
Canadian Diabetes Association
Year
2014
Tongue
English
Weight
230 KB
Volume
38
Category
Article
ISSN
1499-2671

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✍ Fromenty, Bernard; Carrozzo, Rosalba; Shanske, Sara; Schon, Eric A. 📂 Article 📅 1997 🏛 John Wiley and Sons 🌐 English ⚖ 62 KB 👁 1 views

Kearns-Sayre syndrome (KSS) is a sporadic multisystem mitochondrial disorder characterized by progressive external ophthalmoplegia, pigmentary retinopathy, onset before age 20, and severe cardiac conduction defects that can lead to death. KSS patients harbor partial deletions of mitochondrial DNA (⌬