𝔖 Bobbio Scriptorium
✦   LIBER   ✦

Diabetes and hypoglycaemia in young children and mutations in the Kir6.2 subunit of the potassium channel: Therapeutic consequences

✍ Scribed by I Flechtner; P De Lonlay; M Polak


Book ID
117744709
Publisher
Masson Editeur
Year
2006
Tongue
French
Weight
256 KB
Volume
32
Category
Article
ISSN
1262-3636

No coin nor oath required. For personal study only.


πŸ“œ SIMILAR VOLUMES


Adjacent mutations in the gating loop of
✍ Kenju Shimomura; Sarah E. Flanagan; Brittany Zadek; Mark Lethby; Lejla Zubcevic; πŸ“‚ Article πŸ“… 2009 πŸ› John Wiley and Sons 🌐 English βš– 612 KB

K ATP channels regulate insulin secretion from pancreatic b-cells. Loss-and gainof-function mutations in the genes encoding the Kir6.2 and SUR1 subunits of this channel cause hyperinsulinism of infancy and neonatal diabetes, respectively. We report two novel mutations in the gating loop of Kir6.2 wh