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DHBA (2,3-Dihydroxybenzoesäure)-Ausscheidung durch einen enterobactinnegativen multiresistenten Salmonella typhimurium-Wildstamm

✍ Scribed by Dr. W. Rabsch; P. Paul; R. Reissbrodt; Dr. W. Rabsch


Publisher
John Wiley and Sons
Year
1986
Tongue
English
Weight
220 KB
Volume
26
Category
Article
ISSN
0233-111X

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✦ Synopsis


In investigations of iron siderophores produced by different 8dmomlla typhimurium strains we found a strain deficient in enterobactin production. Using microbiological and chemical methods, we detected the production and excretion of 2,3-dihydrobenzoic acid, a metabolite of the enterobactin biosynthesis pathway. The strain was able to produce aerobactin. We suggest that the iron uptake of pathogenic strains can be mediated by aerobactin alone. For a correct enterobactin bioassay it is necessary to use a mutant unable to grow on 2,3-dihydroxybenzoic acid.