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Dextropropoxyphene kinetics after single and repeated oral doses in man

✍ Scribed by K. Brøsen; L. F. Gram; J. Schou; N. E. Larsen; P. Thayssen


Publisher
Springer
Year
1985
Tongue
English
Weight
579 KB
Volume
29
Category
Article
ISSN
0031-6970

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The pharmacokinetic parameters of ibuprofen enantiomers after a single 600 mg dose and repeated 3 x 400 mg doses of Nurofen@ were determined in 12 healthy volunteers. Terminal half-lives were similar for both enantiomers, but plasma levels of S-ibuprofen were higher than those of R-ibuprofen, due to