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Dextran sulfate sodium enhances interleukin-1β release via activation of p38 MAPK and ERK1/2 pathways in murine peritoneal macrophages

✍ Scribed by Ki Han Kwon; Hajime Ohigashi; Akira Murakami


Book ID
116719138
Publisher
Elsevier Science
Year
2007
Tongue
English
Weight
861 KB
Volume
81
Category
Article
ISSN
0024-3205

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## Abstract Thrombin levels increase at sites of vascular injury and during acute coronary syndromes. It is also increased several fold by sepsis with a reciprocal decrease in the anti‐thrombin III levels. In this study we investigate the effects of thrombin on the induction of cyclooxygenase‐2 (CO