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Dexamethasone’s influence on tyrosine hydroxylase activity in the chemoreflex pathway and on the hypoxic ventilatory response

✍ Scribed by V. Joseph; Y. Dalmaz; J. M. Cottet-Emard; J. M. Pequignot

Book ID
106111456
Publisher
Springer
Year
1998
Tongue
English
Weight
296 KB
Volume
435
Category
Article
ISSN
0031-6768

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## Abstract The iron chelator desferrioxamine (DFO) induces accumulation of the hypoxia‐inducible factor (HIF‐1), a transcription factor that up‐regulates genes involved in adaptative responses to hypoxia. This property makes DFO a potential neuroprotector against hypoxic stress. We investigated in