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Dexamethasone Suppression of IL-1β-Induced Cyclooxygenase 2 Expression Is Not Mediated by Lipocortin-1 in A549 Cells

✍ Scribed by S.P. Newman; R.J. Flower; J.D. Croxtall


Book ID
115575050
Publisher
Elsevier Science
Year
1994
Tongue
English
Weight
409 KB
Volume
202
Category
Article
ISSN
0006-291X

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## Abstract In previous study, interleukin‐1β (IL‐1β) has been shown to induce ICAM‐1 expression through MAPKs and NF‐κB in A549 cells. In addition to these pathways, transactivation of non‐receptor tyrosine kinase (Src), PDGF receptors (PDGFRs), and phosphatidylinositol 3‐kinase (PI3K)/Akt has bee