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Dexamethasone Reduced Clonidine-induced Hypoactivity in Mice

โœ Scribed by A. CAPASSO; A. DI GIANNUARIO; A. LOIZZO; S. PIERETTI; L. SORRENTINO


Book ID
118110289
Publisher
Pharmaceutical Press
Year
1996
Tongue
English
Weight
402 KB
Volume
48
Category
Article
ISSN
2042-7158

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Four strains of mice (C57, BALB, DBA, C3H) were used to determine whether genetic factors influence the effects of lithium on hypoactivity induced by a low dose of the alpha 2-adrenoceptor agonist clonidine (0.2 mg/kg). Lithium was administered in the diet for 3-4 weeks at a dosage that produced ave