Dexamethasone-induced adhesion in hepatoma cells: the role of plasminogen activator
β Scribed by FREDIN, BARBARA L.; SEIFERT, SARAH CARLSON; GELEHRTER, THOMAS D.
- Book ID
- 109712918
- Publisher
- Nature Publishing Group
- Year
- 1979
- Tongue
- English
- Weight
- 248 KB
- Volume
- 277
- Category
- Article
- ISSN
- 0028-0836
- DOI
- 10.1038/277312a0
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π SIMILAR VOLUMES
Plasminogen activators are membrane-associated, arginine-specific serine proteases which convert the inactive plasma zymogen plasminogen to plasmin, an active, broad-spectrum serine protease. Plasmin, the major fibrinolytic enzyme in blood, also participates in a number of physiologic functions invo
## Abstract Glucocorticoids induce several phenotypic changes in rat hepatoma cells in tissue culture, including the inhibition of plasminogen activator activity. Variant cell lines resistant to dexamethasone inhibtion of plasminogen activator activity have been isolated using an agarβfibrin overla