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Dexamethasone can potentiate the anti-emetic action of a 5HT3 receptor antagonist on cyclophosphamide induced vomiting in the ferret

✍ Scribed by Hawthorn, J; Cunningham, D


Book ID
109836352
Publisher
Nature Publishing Group
Year
1990
Tongue
English
Weight
877 KB
Volume
61
Category
Article
ISSN
0007-0920

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A total of 28 patients receiving cancer chemotherapy with cisplatin-containing regimens (70-120 mg/ m 2) participated in an evaluation of the efficacy and safety of GR38032F for the prevention of acute nausea and vomiting. GR38032F, a 5HT3 receptor antagonist, was given 30 min prior to cisplatin as