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Dexamethasone blocks arachidonate biosynthesis in isolated hepatocytes and cultured hepatoma cells

✍ Scribed by Carlos A. Marra; Maria J. T. de Alaniz; Rodolfo R. Brenner

Book ID
112773040
Publisher
Springer-Verlag
Year
1986
Tongue
English
Weight
861 KB
Volume
21
Category
Article
ISSN
0024-4201

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πŸ“œ SIMILAR VOLUMES

Inhibition of arachidonate biosynthesis
Inhibition of arachidonate biosynthesis in hepatoma tissue culture cells by 11-deoxycorticosterone-induced factor
✍ Carlos A. Marra; MarΓ­a J. T. Alaniz πŸ“‚ Article πŸ“… 1991 πŸ› Springer 🌐 English βš– 721 KB

In this work it was demonstrated that the incubation of hepatoma cultured cells (HTC 7288 c) with 11-deoxycorticosterone (DOC) ranging from 0 to 10(-4) M concentration provoked a dose-dependent inhibition in the conversion of [1-14C] eicosatrienoic acid to arachidonic acid. This steroid also produce